Caleb A. Massimi

Medicine × Technology × Health Systems

Caleb A. Massimi

A more equitable standard of care.

Medical student at the Icahn School of Medicine at Mount Sinai · machine learning & preventative medicine

About Me

My name is Caleb, and I'm a medical student at the Icahn School of Medicine at Mount Sinai in New York City. I was born in New York, raised in Phoenix, and later returned to New York to attend the University at Buffalo, where I earned my Bachelor's degree in Biological Sciences. My path through different communities and environments has given me a firsthand understanding of how deeply inequality, economic, social, and systemic, shapes people's access to care and quality of life.

Those experiences have become the foundation of my motivation to help build a more equitable and effective healthcare system. I'm driven by a belief that healthcare should serve everyone, not just a privileged few. To me, that means not only improving access but also raising the standard of care through innovation, efficiency, and ethical integration of emerging technologies.

I'm especially passionate about the potential of science, medicine, and artificial intelligence to transform how we understand and deliver care. My goal is to help shape the future of healthcare by adopting these technologies bravely but responsibly, ensuring that progress serves patients first and reflects the highest standards of compassion, integrity, and scientific rigor.

Currently

Last updated: September 2026

I’m beginning my Neurology clerkship after completing OB/GYN and Inpatient Medicine.

Recent Updates

  • September 2026

    Published in Proceedings of the National Academy of Sciences: our study, “Heel-strike mechanics reveal evolutionary trade-offs in hominin bipedalism.” View publication →

  • September 2026

    Beginning my Neurology clerkship after completing OB/GYN and Inpatient Medicine.

  • August 2026

    Featured in VJNeurology discussing the challenges and opportunities in diagnosing isolated REM sleep behavior disorder. Watch the interview →

  • June 2026

    Featured in VJNeurology discussing a two-stage questionnaire- and actigraphy-based screening approach for iRBD. Watch the interview →

  • June 2026

    Beginning clinical clerkships at Mount Sinai, transitioning from preclinical education to direct patient care.

Show 7 older updates Hide older updates
  • June 2026

    Presented validation of the iRBD screening protocol at SLEEP 2026, extending the multicenter cohort findings.

  • May 2026

    Published in Annals of Clinical and Translational Neurology: our iRBD two-stage screening study combining questionnaire and wrist actigraphy achieved 100% specificity across five cohorts. View publication →

  • Early 2026

    Passed USMLE Step 1, completing the final milestone of preclinical medical education.

  • November 2025

    Completing preclinical education and preparing for Step 1, while continuing research at NYU (ADHD) and Mount Sinai (machine learning).

  • July 2025

    Worked on my machine learning model for early detection of REM sleep behavior disorder and co-authored a publication on adult ADHD: Pilot Trial of SDX d-MPH in Adult ADHD .

  • June 2025

    Presented findings from my questionnaire project at SLEEP 2025 in Seattle, Washington and finished my first year of medical school.

  • May 2025

    Completed my duties as M1 class representative, serving my classmates to improve our experience at Mount Sinai.

Research & Publications

2026

Heel-strike mechanics reveal evolutionary trade-offs in hominin bipedalism

Proceedings of the National Academy of Sciences

View Publication →
2026

A Two-Stage Questionnaire and Actigraphy Screening for iRBD in a Multicenter Retrospective Cohort

Annals of Clinical and Translational Neurology

View Publication →

Also presented as “Validation of a Two-Stage Questionnaire and Actigraphy Screening for Isolated REM Sleep Behavior Disorder” — SLEEP 2026 Conference, and at SLEEP 2025 Conference, Seattle, WA.

2025

Pilot Trial of SDX d-MPH in Adult ADHD

Psychopharmacology Bulletin

View Publication →

Interests

Outside medicine and research, I’m interested in technology, photography, numismatics, and the many ways of moving through the world: travel, skiing, sailing, hiking, walking, biking, and fishing.

Travel · interactive Across the Atlantic & Europe A globe-based sketch of movement through Amsterdam, Berlin, Prague, Vienna, and London.